A common characteristic of neurodegenerative diseases such as Huntington’s disease and various forms of dementia is the build-up in the brain of clusters—known as aggregates—of misfolded proteins, such as huntingtin and tau. These aggregates lead to the degradation and eventual death of brain cells and the onset of symptoms. One method that our bodies use […]
Revitalizing Aging Blood System with Anti-Inflammatory Drug A recent study published in Nature Cell Biology has found that an anti-inflammatory drug used for rheumatoid arthritis may be able to reverse some of the effects of aging on the blood system in mice. The drug, called anakinra, has been shown to have rejuvenating effects on the […]
Challenges of Treating Chronic Pain Chronic pain is a complex and difficult condition to treat despite the progress in neuroscience research over the last two decades. A recent overview by Ferreira and colleagues has added to the growing body of evidence on the use of medicines for pain, highlighting the limitations of current medical treatments. […]
Introduction Sickle cell disease is a genetic disorder that affects the hemoglobin in red blood cells. It is caused by a single point mutation in the gene encoding β-globin (HBB), leading to the production of sickle hemoglobin and impaired red-cell function. Patients with sickle cell disease often have vaso-occlusive events, progressive vasculopathy, and chronic hemolytic […]
The social media platform TikTok has seen a surge in the popularity of videos related to attention deficit hyperactivity disorder (ADHD) during the COVID-19 pandemic. The #ADHD channel on the platform now has 2.4 billion views and content related to the mental disorder has been shared by both individuals with no medical credentials and licensed […]
Dapagliflozin is a type of medication known as a sodium-glucose co-transporter 2 (SGLT2) inhibitor that is used to treat type 2 diabetes. It works by helping the kidneys remove excess glucose from the body through the urine, which can help lower blood sugar levels. Several clinical trials have been conducted to investigate the effects of […]
Blood pressure variability is a new and unique factor that is gaining more and more attention in the medical community. It refers to the fluctuation of blood pressure over time, and it can be caused by a variety of factors including stress, exercise, and even the time of day. One important aspect of blood pressure […]
In recent years, mRNA vaccines have garnered significant attention due to their role in the fight against COVID-19. But mRNA vaccines have the potential to do much more than just prevent infectious diseases – they may also have a future role in cancer therapy. But before we dive into the potential of mRNA vaccines in […]
Medication compliance, or the extent to which patients take their prescribed medications as directed, is an important factor in ensuring that patients receive the full benefits of their treatment. However, many patients may not be compliant with their medication regimens for a variety of reasons, such as forgetfulness, fear of side effects, or difficulty affording […]
The dust has finally settled with regards to the Medical Appraisal Template 2022. GP Tools is proud to announce that the form has been implemented in its entirety. There are significant changes from the MAG form and we feel that it is a return to the halcyon days of appraisal when box ticking was yet […]